Abstract Background Neuronal plasticity within the basolateral amygdala (BLA) is fundamental for fear learning.Metaplasticity, the regulation of plasticity states, has emerged as a key mechanism mediating the subsequent impact of emotional and stressful experiences.After mRNA knockdown of synaptic plasticity-related TrkB, we examined the impact of
Abstract Background Implementation theories, models and frameworks offer guidance when implementing and sustaining healthcare evidence-based interventions.However, selection can be challenging given the myriad of potential options.We propose to inform a decision support tool to facilitate the appropriate selection of an implementation theory, model
Due to the fact that commercial wet surimi must be frozen, the adoption of dried surimi or surimi powder has emerged as the favored choice in the surimi industry to reduce costs.However, as surimi experiences the transition to its dried form, changes Fisetin in moisture content can potentially influence quality and shelf life.To determine the optim
Nuclear lamins are important structural and functional proteins in mammalian cells, but little is known about the mechanisms and cofactors that regulate their traffic into the nucleus.Here, we demonstrate that trafficking of lamin A, but not lamin B1, and its assembly into the nuclear envelope are regulated by sorting nexin 6 (SNX6), a major compon
Background.Predicting the resource of friction units, starting from the design stages, should be based on probabilistic models.During the design process, designers must make a reasonable guess about the technical characteristics that the product will have.In relation to the Diabetes Monitoring - Lancets and Lancing Devices stages of operation and o